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Rabbit Anti-CACNG7 Polyclonal Antibody#abs134915

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Description

Catalog-specification	Delivery time	USD price
abs134915-100ug	1-2 Weeks	301.0
abs134915-50ug	1-2 Weeks	201.0

Overview
catalog	abs134915
Other names	The CACNG7 gene encodes the neuronal voltage-gated calcium channel gamma-7 subunit, also known as TARP gamma 7 or transmembrane AMPAR regulatory protein gamma 7. This subunit is a member of the calcium channel voltage-dependent gamma subunit family and contributes to the regulation of calcium influx. The CACNG7 gene is located on the human chromosome 19q13.33 and contains three exons. Variations in this gene have been associated with various neurological disorders, including schizophrenia and autism spectrum disorder. Understanding the function and regulation of the CACNG7 gene may provide important insights into the underlying mechanisms of these disorders.
Source	Rabbit
Specificity	The CACNG7 Antibody can be used to measure the levels of total CACNG7 present in the body. This antibody specifically detects endogenous CACNG7 and can provide accurate information about the levels of this protein in various tissues. It is a highly effective tool that can help researchers to better understand the role of CACNG7 in various biological processes. By utilizing this antibody, scientists can gain important insights into the function of CACNG7 and its potential impact on human health.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Rabbit;Pig;Dog;Horse;Bovine;
Antigen	CACNG7
Application	The recommended dilution for Western Blot is 1:500 to 1:1000, while for IF/ICC it is 1:100 to 1:500. For ELISA using peptide, the suggested dilution range is 1:20000 to 1:40000. It is important to follow these dilution recommendations to ensure appropriate results in your experiments.
Immunogen	A synthesized peptide.
MW	40 KD
Properties
Concentration	1mg/ml
purification	By utilizing SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain quality, it is recommended to store the product at a temperature of -20 °C for a year. It is crucial to avoid subjecting it to multiple freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity only for GRIA1 and GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state.
Tissue specificity	Widely expressed.
Celluar localization	Plasma Membrane;
UniPort	P62955