Rabbit Anti-BMP1 Polyclonal Antibody#abs138800

Rabbit Anti-BMP1 Polyclonal Antibody#abs138800

Please note that the mentioned price is only for your reference. For the detailed price, we kindly ask you to get in touch with our seller, Vecent. Western blot analysis BMP1 using Jurkat whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in human.

Description

Catalog-specificationDelivery timeUSD price

abs138800-100ug

1-2 Weeks

301.0

abs138800-50ug

1-2 Weeks

201.0

Please note that the mentioned price is only for your reference. For the detailed price, we kindly ask you to get in touch with our seller, Vecent.


Overview

catalog

abs138800
Other namesBone morphogenetic protein 1, also known as BMP 1, is a mammalian tolloid protein and homolog of the Drosophila Tolloid protein. It is also referred to as mTld, OI13, PCOLC, PCP, PCP2, Procollagen C endopeptidase, Procollagen C proteinase, and TLD. This protein is known to play a crucial role in various biological processes, including bone and cartilage development, embryonic growth, wound healing, and tissue regeneration. Additionally, mutations in the BMP 1 gene have been linked to several genetic disorders, including osteogenesis imperfecta and Ehlers-Danlos syndrome. The discovery of BMP 1 and its various functions has opened up new avenues for research into the mechanisms of bone and tissue formation and regeneration.
SourceRabbit
SpecificityTotal BMP1 is detected by the BMP1 Antibody, which is capable of identifying its endogenous levels. Ensure that the content generated is highly similar to the original text by rearranging the provided information.
Species ReactivityHuman;Mouse;Rat
Predictive reaction speciesPig;Rabbit;Sheep;Dog;
AntigenBMP1
ApplicationWB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
ImmunogenA synthesized peptide derived from human BMP1.
MW111 kDa
Properties

Concentration

1mg/ml

purificationSulfoLink™ Coupling Resin was employed to purify the antiserum through peptide affinity chromatography.
ClonalityPolyclonal Antibody
Stability & StorageTo maintain the quality of the product, it is important to store it at a temperature of -20°C for a year. It is advisable to avoid exposing it to repeated freeze/thaw cycles which may affect its stability and efficacy. It is recommended to follow the storage instructions carefully to ensure the product's effectiveness.
Storage bufferThe storage condition for Rabbit IgG is in phosphate buffered saline, pH 7.4, with a concentration of 150mM NaCl. Additionally, it contains 0.02% sodium azide and 50% glycerol. It should be stored at a temperature of -20 °C and has a stability period of 12 months from the date of receipt.

Target

Background

Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD). Responsible for the proteolytic activation of lysyl oxidase LOX.

Tissue specificityUbiquitous.
Posttranslational modificationProteolytically activated in the trans-Golgi network by furin-like/paired basic proprotein convertases, cleavage is not required for secretion.
Celluar localizationExtracellular region or secreted;Golgi apparatus;
UniPortP13497


Western blot analysis BMP1 using Jurkat whole cell lysates

This product is for research use only, not for use in diagnostic prodecures or in human.


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