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Rabbit Anti-APOA5 Polyclonal Antibody#abs140862

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Description

Catalog-specification	Delivery time	USD price
abs140862-50ug	1-2 Weeks	201.0
abs140862-100ug	1-2 Weeks	301.0

Overview
catalog	abs140862
Other names	Apo-AV, also known as ApoA-V or Apoa5, is a vital protein found in humans. It is commonly referred to as APOA5_HUMAN or ApoAV. This protein, also referred to as Apolipoprotein A-V or Apolipoprotein A5, is significant for its role in lipid metabolism and its association with various diseases. Additionally, Apo-AV is sometimes recognized as RAP3 or Regeneration Associated Protein 3. This alternative name highlights its involvement in the process of regeneration and cellular recovery. The term "Regeneration-associated protein 3" is another way to refer to this crucial protein. Overall, Apo-AV, ApoA-V, or Apoa5 (collectively referred to as APOA5_HUMAN or ApoAV) plays a fundamental role in lipid metabolism and is also linked to regeneration processes within the human body.
Source	Rabbit
Specificity	The APOA5 Antibody is designed to recognize and bind to total APOA5 protein at levels naturally occurring in the body. Its specificity allows for precise detection of endogenous levels of APOA5.
Species Reactivity	Human
Antigen	APOA5
Application	The working dilution for Western Blotting is in the range of 1:500 to 1:1000. For Immunofluorescence (IF) and Immunocytochemistry (ICC), the recommended dilution is 1:100 to 1:500. In the case of ELISA using peptides, the suggested dilution range is 1:20000 to 1:40000.
Immunogen	A synthesized peptide.
MW	41 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. This process was utilized to ensure high levels of purity and quality in the final product.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure maximum longevity, it is recommended to store the product at a temperature of -20 °C for a duration of up to one year. It is important to note that subjecting the product to repeated freeze/thaw cycles should be avoided at all costs. By following these guidelines, the product can maintain its quality and integrity for an extended period of time.
Storage buffer	This storage solution contains Rabbit IgG in phosphate buffered saline at a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this solution at a temperature of -20 °C. The solution is stable for a period of 12 months from the date of receipt.
Target
Background	A minor apolipoprotein, closely associated with HDL and VLDL, plays a key role in regulating plasma triglyceride levels. This protein exerts its effects through its ability to stimulate lipoprotein lipase activity, which results in the breakdown of triglycerides, and by inhibiting the production of VLDL-TG by the liver without affecting VLDL-apoB production. While it is not a potent activator of LCAT, it does have some influence on cholesterol efflux from macrophages. Overall, this apolipoprotein is an important regulator of lipid metabolism.
Tissue specificity	Liver and plasma.
Posttranslational modification	Phosphorylated by FAM20C in the extracellular medium.
Celluar localization	Endoplasmic reticulum;Extracellular region or secreted;
UniPort	Q6Q788