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Rabbit Anti-AGTR2 Polyclonal Antibody#abs137405

Description

Catalog-specification	Delivery time	USD price
abs137405-100ug	1-2 Weeks	301.0
abs137405-50ug	1-2 Weeks	201.0

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Overview
catalog	abs137405
Other names	The AGTR2 gene encodes for the angiotensin II receptor type 2, also known as AT2 or ATGR2. This receptor is responsible for binding to angiotensin II and has been linked to various physiological processes. The AGTR2 protein is predominantly expressed in fetal tissues and is involved in the regulation of cell growth and differentiation. Interestingly, the expression of AGTR2 is reduced in certain types of cancers, suggesting a possible role in tumor suppression. The AGTR2 protein is also known as MRX88 and has been identified as a potential therapeutic target for various diseases. In conclusion, the angiotensin II receptor type 2 has significant implications for human health and warrants further investigation.
Source	Rabbit
Specificity	The AGTR2 Antibody is capable of identifying total AGTR2 levels, naturally occurring within the body. To craft similar content, the initial text should be repurposed in a way that remains faithful to the original message.
Species Reactivity	Human;Rat
Predictive reaction species	Rabbit;Pig;Dog;Horse;Bovine
Antigen	AGTR2
Application	The recommended dilutions for Western Blot (WB) range from 1:1000 to 1:3000, while for Immunohistochemistry (IHC), the dilution ratio is 1/200. For ELISA using a peptide, the suggested dilution range is 1:20000 to 1:40000. It is important to note that the generated content should be based on the original information provided and not follow the conversation style of ChapGPT.
Immunogen	A synthesized peptide derived from human AGTR2.
MW	41 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. To achieve this, a process was carried out that resulted in the separation of the desirable peptide from other materials present in the antiserum. This led to the production of a highly refined and pure antiserum that is suitable for further use in various applications.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure preservation, keep the store temperature at -20 °C for a year, avoiding any instances of freezing and thawing.
Storage buffer	The Rabbit IgG is available in phosphate buffered saline with a pH of 7.4 and 150mM NaCl. It also contains 0.02% sodium azide and 50% glycerol. For longer storage, it is recommended to keep it at -20 °C, and it remains stable for up to 12 months from the date of receipt.
Target
Background	Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
Tissue specificity	In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Expressed in the cerebellum. Very highly expressed in fetal kidney and intestine.
Celluar localization	Extracellular region or secreted;Plasma Membrane;
UniPort	P50052