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Rabbit Anti-ACP5 Polyclonal Antibody#abs136509

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Description

Catalog-specification	Delivery time	USD price
abs136509-100ug	1-2 Weeks	301.0
abs136509-50ug	1-2 Weeks	201.0

Overview
catalog	abs136509
Description	An iron-containing glycoprotein is encoded by this gene, and it functions as a catalyst in converting orthophosphoric monoester to alcohol and orthophosphate. Among the acid phosphatases, it is the most fundamental form and remains unaffected by inhibition from L(+)-tartrate. Let's generate an alternative content that reflects the provided information with a different approach: This particular gene is responsible for encoding a glycoprotein that possesses iron and serves as a catalyst. Its main function involves converting orthophosphoric monoester into alcohol and orthophosphate. Among the acid phosphatases, it holds the distinction of being the simplest form, and interestingly, it remains unaffected by L(+)-tartrate inhibition.
Other names	Phosphatase 5 acid type; Tartrate-resistant acid phosphatase 5; Tartrate-resistant acid phosphatase 5 variant; ACP5 enzyme; EC 3.1.3.2; MGC117378 protein; PPA5_HUMAN gene; acid phosphatase resistant to tartrate in serum band 5; SPENCDI protein; T5ap enzyme; Tartrate-resistant acid ATPase; Precursor of tartrate-resistant acid phosphatase type 5; Tartrate-resistant acid ATPase; Tartrate-resistant acid phosphatase type 5; Tartrate-resistant acid phosphatase type 5 precursor; TR AP enzyme; TR-AP protein; TRACP 5 variant; TRAP enzyme; TrATPase protein; Type 5 acid phosphatase.
Source	Rabbit
Specificity	The ACP5 Antibody is capable of detecting the total amount of ACP5 that occurs naturally within the body. The levels of this protein can be measured accurately using this antibody, allowing for improved diagnostic and therapeutic approaches. Overall, this antibody plays a significant role in the analysis of ACP5 and its impact on various biological processes within the body.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Rabbit;
Antigen	ACP5
Application	IHC 1:50-1:200, ELISA (peptide) 1:20000-1:40000, WB 1:500-1:2000. These are dilution ratios commonly used in scientific experiments. It is important to carefully determine the appropriate dilution for each assay to ensure accurate results. For Western blot (WB), a dilution range of 1:500-1:2000 is typically used to detect specific proteins. Immunohistochemistry (IHC) assays usually require a dilution range of 1:50-1:200 to visualize target antigens in tissue samples. ELISA assays using peptide antigens usually require higher dilutions, typically ranging from 1:20000 to 1:40000. These dilution ratios are crucial for obtaining optimal signal-to-noise ratios and reliable data.
Immunogen	A synthesized peptide derived from human ACP5.
MW	37kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.
Celluar localization	Cytosol;Extracellular region or secreted;Lysosome;
UniPort	P13686