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Rabbit Anti-AAT1 Polyclonal Antibody#abs138721

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Description

Catalog-specification	Delivery time	USD price
abs138721-100ug	1-2 Weeks	301.0
abs138721-50ug	1-2 Weeks	201.0

Overview
catalog	abs138721
Other names	AAT 1, also known as AAT-1, AAT1 alpha, AAT1, and AAT1_HUMAN, is a protein that plays a crucial role in various physiological processes. It is also referred to as AMY 1 associating protein expressed in testis 1 or AMY-1-associating protein expressed in testis 1. The protein is encoded by the Chromosome 3 open reading frame 15 gene and is involved in MYCBP binding protein. AAT 1 is a vital protein that is present in numerous tissues and cells. Its functions range from regulating gene expression, promoting cell growth, and providing protection against various stressors. Understanding the role of AAT 1 in the body can help develop new therapeutic approaches for treating various diseases.
Source	Rabbit
Specificity	The AAT1 Antibody is capable of detecting the overall levels of AAT1 that exist naturally within an organism. To produce similar content with a different structure, one might write, "By binding to AAT1, the AAT1 Antibody can recognize and measure the total amount of this protein that is present in an organism's system."
Species Reactivity	Human
Antigen	AAT1
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human AAT1.
MW	71 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure preservation, it is recommended to store the item at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting it to multiple cycles of freezing and thawing.
Storage buffer	The rabbit IgG is stored in a solution of phosphate buffered saline with a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. The recommended storage temperature is -20 °C, where it remains stable for up to 12 months from the date of receipt.
Target
Background	May regulate cilium motility through its role in the assembly of the axonemal radial spokes.
Tissue specificity	Isoform 1 is strongly expressed in the liver. Isoform 4 is widely expressed, but strongly expressed in all spermatogenesis-related tissues, including the testis, the epithelium of cauda and the corpus epididymis, as well as the spermatid and mature sperm. Isoform 4 is also expressed in Leydig cells. Isoform 3 is expressed in the testis.
Posttranslational modification	Isoform 4 is phosphorylated by PKA.
Celluar localization	Cytoskeleton;Mitochondrion;
UniPort	Q7Z4T9