Tris Base

THAM, also known as Tris base, is extensively utilized in biological buffers and buffer formulations such as TAE and TBE buffers. It possesses a pKa value of 8.06, making it particularly valuable in biology and biochemistry laboratories due to its buffering capabilities within the typical physiological pH range of most living organisms (pH 7.0-9.0). However, caution must be exercised when studying proteins as Tris has been observed to potentially interfere with the activity of several enzymes.

A buffer of excellent quality that is suitable for use in the range of pH 7-9 is required. Please provide a similar description by rearranging the given information, while ensuring that the generated content stays true to the original text.

99%,BR grade

Store at RT,2 years

Scientific reagent

Tris base, also known as 2-Amino-2-(hydroxymethyl)-1,3-propanediol, is a compound that is commonly used in various applications. This versatile chemical is renowned for its ability to act as a buffering agent and stabilize pH levels in a wide range of solutions. Tris base is also utilized in the field of molecular biology as a component of buffer systems to maintain a constant pH during experiments. Additionally, it finds applications in the production of detergents, cosmetics, and pharmaceuticals. Due to its versatile nature and numerous benefits, Tris base continues to be a popular choice among researchers and professionals in various industries. Its unique molecular structure and properties make it an essential ingredient in many scientific and commercial endeavors requiring optimal pH control and stability.

This substance exhibits varying solubilities in different solvents. It readily dissolves in water at a concentration of 550 mg/ml. Additionally, it is soluble in ethylene glycol (79.1 mg/ml), methanol (26 mg/ml), anhydrous ethanol (14.6 mg/ml), 95% ethanol (22 mg/ml), DMF (14 mg/ml), acetone (2 mg/ml), and ethyl acetate (0.5 mg/ml). Its solubility decreases in olive oil (0.4 mg/ml) and chloroform (0.05 mg/ml). Furthermore, it is soluble in alkaline solutions.