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Rabbit Anti-SOX1 Polyclonal Antibody#abs137673

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Description

Catalog-specification	Delivery time	USD price
abs137673-100ug	1-2 Weeks	301.0
abs137673-50ug	1-2 Weeks	201.0

Overview
catalog	abs137673
Other names	The gene known as Sex Determining Region Y box 1 is also referred to as sox1 or SOX1_HUMAN. This gene encodes a transcription factor called Sox-1, which contains a SRY box that is related to the SRY (SRY Box Containing Gene 1) gene. In humans, this gene plays an important role in the development of the central nervous system. With its high similarity to SRY, SOX1 is involved in cellular proliferation and differentiation during embryonic development. Additionally, mutations in SOX1 have been linked to various neurological disorders, such as mental retardation and cerebral palsy.
Source	Rabbit
Specificity	The total expression of endogenous SOX1 can be detected using the SOX1 Antibody. Let me create a revised content based on the original text information: The detection of total SOX1 levels within the organism's own cellular composition is made possible through the application of the SOX1 Antibody.
Species Reactivity	Human
Predictive reaction species	Pig;Bovine;Dog
Antigen	SOX1
Application	Based on the original text information, the recommended dilutions for Western Blot are between 1:1000-3000, while for Immunohistochemistry it is 1:200, and for ELISA using peptide, it should be between 1:20000-1:40000. It is important to note that these are just recommended dilutions and optimization may be required for each specific experiment. Nonetheless, these dilutions have been widely used by researchers and have yielded satisfactory results. When conducting experiments, it is crucial to carefully consider the appropriate dilution factors to ensure accurate and reliable data.
Immunogen	A synthesized peptide derived from human SOX1.
MW	50 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed in purifying the antiserum through peptide affinity chromatography. Please create an alternate version of the provided information while maintaining its original context.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to keep the store at -20 °C for a duration of one year. To maintain the product's integrity, it is important to avoid subjecting it to repeated freeze/thaw cycles.
Storage buffer	This product consists of Rabbit IgG dissolved in a solution of phosphate buffered saline at pH 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this product at -20 °C to ensure stability for up to 12 months from the date of receipt.
Target
Background	Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Tissue specificity	Mainly expressed in the developing central nervous system.
Celluar localization	Nucleus;
UniPort	O00570