Rabbit Anti-SH3RF3 Polyclonal Antibody#abs134806
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Description
| Catalog-specification | Delivery time | USD price |
abs134806-100ug | 1-2 Weeks | 301.0 |
abs134806-50ug | 1-2 Weeks | 201.0 |
Please note that the price mentioned above is for your reference only. For detailed pricing information, please get in touch with our seller Vecent. Kindly bear in mind that the content generated using ChapGPT may not be similar and instead, the language model will produce entirely different text.
| Overview | |
catalog | abs134806 |
| Other names | SH3 domain-containing RING finger protein 3, also known as POSH2 or SH3 multiple domains protein 4 (SH3MD4), is a highly abundant protein in human cells. It is encoded by the SH3RF3 gene and plays a crucial role in various cellular processes. The SH3R3_HUMAN protein consists of multiple SH3 domains, which are protein interaction modules involved in signal transduction and protein-protein interactions. Numerous SH3s can be found in the human proteome, indicating the importance of these domains in cellular function. SH3 domain-containing proteins, such as SH3RF3, are involved in diverse signaling pathways, including those regulating cell growth, differentiation, and apoptosis. The SH3MD4 protein is characterized by its RING finger domain, which confers E3 ubiquitin ligase activity. This activity allows SH3RF3 to regulate the degradation of target proteins through the ubiquitin-proteasome pathway. In conclusion, SH3 domain-containing RING finger protein 3 (POSH2 or SH3MD4) is a versatile protein with multiple SH3 domains that plays a critical role in various cellular processes, including signal transduction and protein degradation. Its diverse functions highlight its importance in maintaining cellular homeostasis. |
| Source | Rabbit |
| Specificity | The SH3RF3 Antibody is capable of detecting total SH3RF3 levels that exist naturally within the system. The detected levels are entirely endogenous in nature, meaning they are present without any external influence. |
| Species Reactivity | Human;Mouse |
| Antigen | SH3RF3 |
| Application | The dilution range for Western Blot is 1:500 to 1:1000, for IF/ICC it is 1:100 to 1:500, and for ELISA (peptide) it is 1:20000 to 1:40000. |
| Immunogen | A synthesized peptide. |
| MW | 92 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | Using SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. A highly similar version of this information could be: Through the method of peptide affinity chromatography, the antiserum was purified utilizing SulfoLink™ Coupling Resin. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To preserve the quality, the recommended storage condition for one year is -20 °C. It is important to prevent the occurrence of repeated freeze/thaw cycles. Remember to follow these guidelines for optimal storage of the product. |
| Storage buffer | The Rabbit IgG is stored in a solution of phosphate buffered saline at a neutral pH level of 7.4, containing 150mM of NaCl and 0.02% sodium azide as preservatives, along with 50% glycerol for optimal storage conditions at -20°C. It is advised to keep the solution at this temperature to maintain its stability for up to 12 months from the date of receipt. |
Target | |
| UniPort | Q8TEJ3 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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