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Rabbit Anti-RPS19 Polyclonal Antibody#abs140759

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Description

Catalog-specification	Delivery time	USD price
abs140759-50ug	1-2 Weeks	201.0
abs140759-100ug	1-2 Weeks	301.0

Overview
catalog	abs140759
Other names	The 40S ribosomal protein S19, also known as ribosomal protein S19 or rps19, is essential for efficient protein synthesis. Mutations in this protein have been linked to Diamond-Blackfan anemia (DBA), a rare genetic disorder that affects the production of red blood cells. DBA is caused by mutations in various ribosomal protein genes, including DBA1, which encodes for S19. The human gene symbol for S19 is HGNC:10402, and its protein product is designated as RS19_HUMAN. Understanding the function and role of S19 is critical for advancing our understanding of DBA and other genetic disorders that affect protein synthesis.
Source	Rabbit
Specificity	Total RPS19 levels are detected by the RPS19 Antibody, which targets endogenous levels. The antibody helps in the identification of RPS19 in sample analysis. Reordering the content maintains the original message.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Sheep;Dog;Bovine;Horse
Antigen	RPS19
Application	The dilution ranges for WB, IHC, IF/ICC, and ELISA (peptide) are as follows: WB 1:500~1:1000, IHC 1:50~1:200, IF/ICC 1:100-1:500, and ELISA (peptide) 1:20000-1:40000. It is important to note that these ranges represent the recommended dilutions for optimal results in each assay. By adjusting the dilution factors within these ranges, researchers can fine-tune and optimize their experiments for specific targets and applications. Please ensure to follow the provided guidelines carefully to obtain accurate and reliable results.
Immunogen	A synthesized peptide.
MW	16 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. This resulted in a purified form of the antiserum that was highly effective in targeting specific peptides.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage, it is recommended to keep the store at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the stored items to repeated freeze/thaw cycles, as this can negatively impact their quality and integrity. Following these guidelines will ensure the preservation of the products.
Storage buffer	This is a description of Rabbit IgG in a buffer that includes phosphate and saline, with a neutral pH of 7.4. The solution also contains 150mM of NaCl, 0.02% of sodium azide and 50% of glycerol. Storage of this substance is recommended at temperatures below -20 °C, and its shelf life is 12 months from receipt.
Target
Background	Required for pre-rRNA processing and maturation of 40S ribosomal subunits.
Tissue specificity	Higher level expression is seen in the colon carcinoma tissue than normal colon tissue.
Celluar localization	Cytosol;Extracellular region or secreted;Nucleus;
UniPort	P39019