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Rabbit Anti-LONP2 Polyclonal Antibody#abs140459

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Description

Catalog-specification	Delivery time	USD price
abs140459-100ug	1-2 Weeks	301.0
abs140459-50ug	1-2 Weeks	201.0

Overview
catalog	abs140459
Other names	Peroxisomal Lon protease, also known as Lon peptidase 2 or Lon protease homolog 2, plays a significant role in cellular proteolysis. It is an essential enzyme involved in maintaining the quality control of mitochondrial proteins. With its functional similarity to the Lon protease, this peroxisomal Lon protease homolog 2, also referred to as Lon protease-like protein 2, exerts its activity within the peroxisomes. The Lon protease homolog 2 peroxisomal variant, identified as LONP or lonp2, belongs to the Lon protease family and exhibits a high degree of conservation in its structure and function. The human LONP2 protein, encoded by the LONP2_HUMAN gene, shares sequence similarities with the Lon protease, thus participating in essential cellular processes. Additionally, the LONP2 protein is sometimes referred to as MGC4840, highlighting its association and identification within the MGC gene collection. Its peroxisomal localization indicates that this protease contributes to maintaining peroxisomal homeostasis and function. In summary, the peroxisomal Lon protease, also known as Lon protease homolog 2, plays a critical role in protein turnover within peroxisomes. With its similarity to the Lon protease, the LONP2 protein is involved in crucial cellular processes and contributes to peroxisomal maintenance and function.
Source	Rabbit
Specificity	The endogenous levels of total LONP2 can be detected using the LONP2 Antibody. To ensure accuracy, it is important to rearrange the content without relying on ChapGPT's generated responses.
Species Reactivity	Human
Predictive reaction species	Zebrafish;Chicken;Rabbit;Xenopus;Dog;Horse;Bovine;Sheep;Pig
Antigen	LONP2
Application	WB 1:1000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human LONP2.
MW	95kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized to perform peptide affinity chromatography for the purification of the antiserum. Let me provide you with a rephrased statement while preserving the original information. By utilizing SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is recommended to keep the item at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the item to repeated freeze/thaw cycles. Taking these precautions will help maintain the quality and stability of the product. Please adhere to the aforementioned guidelines for proper storage.
Storage buffer	The Rabbit IgG solution is formulated with phosphate buffered saline at pH 7.4, along with 150mM of NaCl, 0.02% sodium azide, and 50% glycerol. For storage, it is recommended to keep it at a temperature of -20°C. This solution is stable for up to 12 months from the date of receipt.
Target
Background	ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import (By similarity). May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.
Celluar localization	Nucleus;Peroxisome;
UniPort	Q86WA8