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Rabbit Anti-KIR2DL5A Polyclonal Antibody#abs139120

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Description

Catalog-specification	Delivery time	USD price
abs139120-100ug	1-2 Weeks	301.0
abs139120-50ug	1-2 Weeks	201.0

Overview
catalog	abs139120
Other names	The CD158F molecule, also known as CD158f1 or KI2LA_HUMAN, belongs to the killer cell immunoglobulin-like receptor family. Specifically, it is a member of the KIR2DL5A subtype, which is characterized by a long cytoplasmic tail and two domains. This receptor is expressed on the surface of natural killer cells and plays a critical role in regulating their activity and response to various stimuli. In addition to its full name, CD158F is also known by several other names, including killer cell immunoglobulin-like receptor KIR2DL5A, killer-cell Ig-like receptor, KIR2DL5, KIR2DL5.1, KIR2DL5.3, KIR2DL5A, and KIR2DL5B. Despite these different names, they all refer to the same protein and its function within the immune system. Overall, CD158F and its related receptors are essential for the proper functioning of natural killer cells and other components of the innate immune system. By recognizing and responding to various signals, they help to protect the body from harmful pathogens and abnormal cells, such as those associated with cancer.
Source	Rabbit
Specificity	The endogenous levels of total KIR2DL5A can be accurately identified using the KIR2DL5A Antibody. To ensure reliable detection, this antibody is specifically designed to target KIR2DL5A and can effectively recognize its presence. By detecting the endogenous levels of total KIR2DL5A, this antibody offers valuable insights into its expression and regulation in various biological systems. It is a highly reliable tool for studying the function and activity of KIR2DL5A, enabling researchers to further understand its involvement in different physiological and pathological processes.
Species Reactivity	Human;Rat
Antigen	KIR2DL5A
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human KIR2DL5A.
MW	41 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed for peptide affinity chromatography to purify the antiserum. Let me generate a highly similar content by rearranging the above information: The purification process of the antiserum involved the use of SulfoLink™ Coupling Resin for peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the longevity of the product, it is advised to store it at a temperature of -20 °C for up to a year. It is important to avoid any instances of freezing and thawing, as repeated cycles can have a detrimental effect on the quality of the product. Thus, proper storage is crucial for maintaining the product's integrity and effectiveness.
Storage buffer	The storage conditions for Rabbit IgG are as follows: it should be stored at a temperature of -20 °C. The IgG should be kept in a solution of phosphate buffered saline with a pH of 7.4. The solution should also contain 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to note that the stability of the IgG is guaranteed for a period of 12 months from the date of receipt.
Target
Background	Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.
Celluar localization	Plasma Membrane;
UniPort	Q8N109