Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-ICAM3 Polyclonal Antibody#abs137470

Please note that the price mentioned above is only for your reference. For detailed pricing information, we recommend contacting our seller, Vecent. Western blot analysis ICAM3 using HepG2 whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in human.

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs137470-100ug	1-2 Weeks	301.0
abs137470-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. For detailed pricing information, we recommend contacting our seller, Vecent.

Overview
catalog	abs137470
Other names	ICAM-3, also known as CD50 or CDW50, is a cell surface glycoprotein that plays a crucial role in intercellular adhesion. It is encoded by the ICAM3 gene and is commonly found in humans. ICAM-3 serves as a receptor for cell adhesion molecules and is involved in various cellular processes. Another name for ICAM-3 is ICAM-R, which stands for ICAM receptor. With its diverse functions, ICAM-3 contributes significantly to the regulation of cell-to-cell interactions within the immune system.
Source	Rabbit
Specificity	The detection of total ICAM3 is accomplished by the ICAM3 Antibody, which is capable of identifying endogenous levels of this protein. To produce a similar content based on the original text information, but in a distinct manner generated by a language model, we can rephrase it as follows: Endogenous levels of total ICAM3 can be accurately identified using the ICAM3 Antibody. This antibody specifically recognizes ICAM3 protein, aiding in the detection process.
Species Reactivity	Human;Mouse
Antigen	ICAM3
Application	1:1000-3000，；，1:100-1:500，；（ELISA），1:20000-1:40000。，。
Immunogen	A synthesized peptide derived from human ICAM3.
MW	120 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized in purifying the antiserum through peptide affinity chromatography. This procedure enabled the separation of unwanted substances, resulting in a purified antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is recommended to store the product at a temperature of -20 °C for up to one year. It is also important to refrain from subjecting the product to repeated freeze/thaw cycles, as this may have a negative impact on its quality and effectiveness. So, proper storage is critical for maintaining the potency and stability of the product.
Storage buffer	The Rabbit IgG solution comes in a phosphate buffered saline with a neutral pH of 7.4 and contains 150mM of NaCl, along with 0.02% of sodium azide and 50% of glycerol. It should be stored at a temperature of -20 °C to ensure stability, and the shelf life of the solution is 12 months from the date of receipt.
Target
Background	Leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) binds to ICAM proteins, which include ICAM3 as a ligand for integrin alpha-D/beta-2. Working together with integrin alpha-L/beta-2, these proteins play a role in the phagocytosis of apoptotic neutrophils by macrophages. This information was published in PubMed in 1992 (PubMed:1448173) and was later supported by a study published in 2013 (PubMed:23775590).
Tissue specificity	Leukocytes.
Posttranslational modification	Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues.N-glycosylated; glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains.
Celluar localization	Extracellular region or secreted;Plasma Membrane;
UniPort	P32942