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Rabbit Anti-GLIS3 Polyclonal Antibody#abs137226

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Description

Catalog-specification	Delivery time	USD price
abs137226-100ug	1-2 Weeks	301.0
abs137226-50ug	1-2 Weeks	201.0

Overview
catalog	abs137226
Other names	GLIS3; Zinc finger protein GLIS3; FLJ90578; MGC33662; ZNF515; Zinc finger protein 515; GLI similar 3; GLIS family zinc finger 3; GLI SIMILAR PROTEIN 3; OK/KNS-cl.4; FLJ38999. These are the various names associated with the gene FLJ38999. The protein encoded by this gene belongs to the GLI superfamily of transcription factors and contains zinc finger domains. It is involved in regulating gene expression and plays a crucial role in various cellular processes. Additionally, it has been linked to several diseases and disorders. The protein GLIS3 has similar characteristics to GLI proteins and possesses zinc finger motifs, which are crucial for its DNA-binding activity. Studies have identified its involvement in different biological pathways, making it an interesting target for further research.
Source	Rabbit
Specificity	Endogenous levels of total GLIS3 can be accurately detected using the GLIS3 Antibody. To ensure precise results, it is important to note that the antibody specifically targets endogenous GLIS3 levels. By utilizing this antibody, researchers can assess and measure the total amount of GLIS3 present in a sample. This information bears significance in studies related to GLIS3 and its related functions, providing insights into its role in various biological processes. The GLIS3 Antibody is a valuable tool in understanding the mechanisms and functions associated with GLIS3. Staying true to the original text, the content has been rearranged while maintaining its essence.
Species Reactivity	Human
Predictive reaction species	Sheep;Rabbit;Horse;Pig;
Antigen	GLIS3
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human GLIS3.
MW	84 kDa
Properties
Concentration	1mg/ml
purification	We purified the antiserum through peptide affinity chromatography, utilizing SulfoLink™ Coupling Resin for the process.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain optimum conditions, the product should be stored at a temperature of -20 °C for a duration of one year. It is crucial to prevent the product from undergoing multiple freeze/thaw cycles.
Storage buffer	This product is a solution of Rabbit IgG in a buffer of phosphate saline with a pH value of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this solution at -20°C and it will remain stable for up to 12 months from the date of receipt.
Target
Background	Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5'-GACCACCCAC-3' (By similarity).
Tissue specificity	In the adult, expressed at high levels in the kidney and at lower levels in the brain, skeletal muscle, pancreas, liver, lung, thymus and ovary.
Celluar localization	Nucleus;
UniPort	Q8NEA6