Rabbit Anti-FGRL1 Polyclonal Antibody#abs135003
Please note that the price shown here is for reference purposes only. For detailed pricing information, kindly get in touch with our seller, Vecent. It is important to note that the aforementioned price is subject to change and may not be final. Therefore, it is recommended that you confirm the...
Description
| Catalog-specification | Delivery time | USD price |
abs135003-100ug | 1-2 Weeks | 301.0 |
abs135003-50ug | 1-2 Weeks | 201.0 |
Please note that the price shown here is for reference purposes only. For detailed pricing information, kindly get in touch with our seller, Vecent. It is important to note that the aforementioned price is subject to change and may not be final. Therefore, it is recommended that you confirm the price with our seller before proceeding with any transaction. Thank you.
| Overview | |
catalog | abs135003 |
| Other names | The FGF homologous factor receptor, also known as FGF receptor like protein 1 or FGFR-like protein 1, plays a vital role in various cellular processes. It is encoded by the gene FGFR5 and belongs to the family of fibroblast growth factor receptors. The FGFR5 gene is located on chromosome 4q21 and is expressed in various tissues, including the brain, heart, and skeletal muscles. The FGFR5 protein shares sequence homology with other FGF receptors and contains three extracellular immunoglobulin-like domains, a transmembrane domain, and a cytoplasmic domain with tyrosine kinase activity. It acts as a receptor for FGF ligands and plays a crucial role in the regulation of cell growth, differentiation, and development. Aberrations in the FGFR5 gene have been associated with various diseases, including cancer and skeletal dysplasia. Targeting FGFR5 with antibodies or small molecule inhibitors has emerged as a promising therapeutic strategy for the treatment of cancer. In summary, FGFR5 is a crucial member of the FGF receptor family, which plays a vital role in the regulation of various cellular processes. Its dysregulation has been linked to various diseases, and targeting it has emerged as a promising therapeutic strategy for cancer treatment. |
| Source | Rabbit |
| Specificity | The endogenous levels of total FGRL1 can be accurately detected by using the FGRL1 antibody. Let me provide you with information on how this antibody recognizes and quantifies FGRL1 proteins in a sample. |
| Species Reactivity | Human;Mouse |
| Antigen | FGRL1 |
| Application | ，。： ELISA(peptide) 1:20000-1:40000，WB 1:500~1:1000，IF/ICC 1:100-1:500。 |
| Immunogen | A synthesized peptide. |
| MW | 54 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | Purification of the antiserum was achieved through the use of SulfoLink™ Coupling Resin in conjunction with peptide affinity chromatography. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | The recommended storage condition is at a temperature of -20 °C for a duration of one year. It is crucial to avoid subjecting the item to multiple freeze/thaw cycles. |
| Storage buffer | This product contains Rabbit IgG suspended in a solution of phosphate buffered saline with a pH of 7.4. The solution is supplemented with 150mM NaCl and 0.02% sodium azide as preservatives. Additionally, 50% glycerol is added to the solution. It is recommended to store this product at a temperature of -20 °C. The stability of this product is guaranteed for a period of 12 months from the date of receipt. |
Target | |
Background | Has a negative effect on cell proliferation. |
| Tissue specificity | Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen. |
| Celluar localization | Golgi apparatus;Plasma Membrane; |
| UniPort | Q8N441 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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