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Rabbit Anti-F13B Polyclonal Antibody#abs138921

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Description

Catalog-specification	Delivery time	USD price
abs138921-100ug	1-2 Weeks	301.0
abs138921-50ug	1-2 Weeks	201.0

Overview
catalog	abs138921
Other names	The proteins Coagulation factor XIII, A2 polypeptide and Coagulation factor XIII, B polypeptide, also known as F13A2 and F13B respectively, play important roles in blood coagulation. F13A2 is essential for the stabilisation of fibrin clots, while F13B is involved in the activation of F13A2. Both polypeptides are encoded by separate genes located on chromosome 6. Together, they make up the coagulation factor XIII complex, also known as FXIIIB. The FXIIIB complex plays a crucial role in the final stages of blood clotting, ensuring proper wound healing and hemostasis. Understanding the functions of these proteins is important for the diagnosis and treatment of blood clotting disorders.
Source	Rabbit
Specificity	The detection of endogenous levels of total F13B is facilitated by the F13B antibody.
Species Reactivity	Human
Antigen	F13B
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human F13B.
MW	76kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to multiple freeze/thaw cycles.
Storage buffer	The Rabbit IgG is suspended in a solution of phosphate buffered saline with a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. To maintain its stability, it should be stored at a temperature of -20 °C. It can be safely stored for a period of 12 months starting from the date of receipt.
Target
Background	Factor XIII's B chain does not possess any catalytic activity; rather, it serves to stabilize the A subunits and regulate the formation rate of transglutaminase by thrombin.
Celluar localization	Extracellular region or secreted;
UniPort	P05160