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Rabbit Anti-CALM1 Polyclonal Antibody#abs135839

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Description

Catalog-specification	Delivery time	USD price
abs135839-100ug	1-2 Weeks	301.0
abs135839-50ug	1-2 Weeks	201.0

Overview
catalog	abs135839
Source	Rabbit
Specificity	The endogenous levels of total CALM1 can be detected using the CALM1 Antibody. It is important to note that the generated content should be based on the original text information but rearranged in a highly similar manner.
Species Reactivity	Human;Mouse;Rat
Antigen	CALM1
Application	For western blot, the recommended dilution range is between 1:500 and 1:2000. When it comes to immunohistochemistry, it's suggested to dilute between 1:50 and 1:200. For immunofluorescence and immunocytochemistry, a dilution range of 1:100 to 1:500 is recommended. Lastly, for ELISA using a peptide, the suggested dilution is between 1:20000 to 1:40000.
Immunogen	A synthesized peptide derived from human CALM1.
MW	17kDa
Properties
Concentration	1mg/ml
purification	Utilizing SulfoLink™ Coupling Resin, the antiserum underwent peptide affinity chromatography for purification purposes.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is advised to keep it stored at a temperature of -20 °C for up to one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles as this can have an adverse effect on its properties and efficacy. Therefore, do take note to handle the product with care and ensure it is stored properly for optimal shelf life.
Storage buffer	This solution contains Rabbit IgG in phosphate buffered saline with a pH of 7.4 and 150mM NaCl. It also has a stabilizer of 0.02% sodium azide and 50% glycerol for storage at -20 °C. It is important to note that this product is stable for up to 12 months from the date of receipt.
Target
Background	Calmodulin plays a crucial role in the regulation of numerous proteins, including enzymes, ion channels, aquaporins, and more, by binding to calcium. One significant effect of the calmodulin-calcium complex is the activation of various protein kinases and phosphatases. Moreover, it participates in a genetic pathway alongside CCP110 and centrin, which controls the centrosome cycle and facilitates progress in cytokinesis. By rearranging the provided information, a similar content is created, maintaining the essence of the original text.
Posttranslational modification	Ubiquitination results in a strongly decreased activity.Phosphorylation results in a decreased activity.
Celluar localization	Cytoskeleton;Mitochondrion;Plasma Membrane;
UniPort	P0DP25