Rabbit Anti-Adrenergic Receptor Alpha-1B Polyclonal Antibody#abs138318
Please note that the mentioned price serves as a reference only. For the detailed price, we suggest reaching out to our seller, Vecent. Western blot analysis Adrenergic Receptor α-1B using COS7 whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in...
Description
| Catalog-specification | Delivery time | USD price |
abs138318-100ug | 1-2 Weeks | 301.0 |
abs138318-50ug | 1-2 Weeks | 201.0 |
Please note that the mentioned price serves as a reference only. For the detailed price, we suggest reaching out to our seller, Vecent.
| Overview | |
catalog | abs138318 |
| Other names | The ADA1B_HUMAN gene encodes the Adrenergic alpha 1B receptor, also known as ADRA1, Adra 1b, ADRA1B, or Alpha 1B adrenoceptor. This receptor is a member of the alpha-1 adrenergic receptor family, which mediates the physiological effects of the neurotransmitter epinephrine (adrenaline) and the hormone norepinephrine (noradrenaline) on target cells. The Alpha-1B adrenergic receptor is expressed in a variety of tissues, including the cardiovascular system, smooth muscle, and the central nervous system. Activation of the receptor by its ligands leads to vasoconstriction, increased blood pressure, and other physiological responses. Dysfunction of the receptor has been linked to various diseases, such as hypertension, migraine, and diabetes. Therefore, understanding the molecular mechanisms of this receptor is important for the development of new therapeutic interventions. |
| Source | Rabbit |
| Specificity | The antibody against Adrenergic Receptor α-1B recognizes the total amount of endogenous Adrenergic Receptor α-1B protein. |
| Species Reactivity | Human;Mouse;Rat |
| Predictive reaction species | Rabbit |
| Antigen | Adrenergic Receptor α-1B |
| Application | WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000 |
| Immunogen | α-1B 。，。 |
| MW | 56 kDa |
| Properties | |
Concentration | 1mg/ml |
| purification | Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. A highly pure and concentrated antiserum was obtained through this process. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | The recommended storage condition for this product is -20 °C for a duration of one year. It is important to avoid subjecting the product to multiple freeze/thaw cycles during storage. |
| Storage buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
Target | |
Background | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes. |
| Celluar localization | Nucleus;Plasma Membrane; |
| UniPort | P35368 |
Western blot analysis Adrenergic Receptor α-1B using COS7 whole cell lysates
This product is for research use only, not for use in diagnostic prodecures or in human.
Hot Tags: rabbit anti-adrenergic receptor alpha-1b polyclonal antibody#abs138318, China rabbit anti-adrenergic receptor alpha-1b polyclonal antibody#abs138318 suppliers
Send Inquiry
You Might Also Like
