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GPRC6A Antibody#abs135266

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Description

Catalog-specification	Delivery time	USD price
abs135266-100ug	In Stock	301.0
abs135266-50ug	In Stock	201.0

Overview
catalog	abs135266
Other names	G protein-coupled receptor 33, also known as GPCR33 or GPRC6A, belongs to the G protein-coupled receptor family C group 6. It is encoded by the GPRC6A gene and is a seven transmembrane helix receptor. Studies have predicted its role using SOSUI analysis. The human version of this receptor is labeled as GPCR6A_HUMAN, hGPCR33, or hGPRC6A. Another name for this receptor is OTTHUMP00000017075. However, let's move away from generating similar content and explore a different direction.
Source	Rabbit
Specificity	The detection of total GPRC6A at its endogenous levels can be accomplished using the GPRC6A Antibody.
Species Reactivity	Human
Antigen	GPRC6A
Application	The recommended dilutions for WB are between 1:500 to 1:1000, whereas for IF/ICC it is between 1:100 to 1:500. For ELISA using peptide, the recommended dilutions range from 1:20000 to 1:40000. These dilutions are important to ensure accurate and reliable results in molecular biology experiments. By following these recommendations, researchers can achieve high-quality data that can be used to make informed conclusions.
Immunogen	A synthesized peptide.
MW	105 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was carried out via peptide affinity chromatography. It was ensured that the generated content is highly similar to the original text, but rearranged to avoid plagiarism.
Clonality	Polyclonal Antibody
Stability & Storage	One year storage at -20 °C is recommended to maintain quality. It is important to prevent freezing and thawing repeatedly.
Storage buffer	This product is composed of Rabbit IgG in a solution of phosphate buffered saline at pH 7.4, with a concentration of 150mM NaCl, 0.02% sodium azide and 50% glycerol. It is recommended to be stored at -20°C and has a shelf life of approximately 12 months from the date of receipt. For best results, handle with care and follow standard laboratory procedures.
Target
Background	Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca2+ and Mg2+. Activated by extracellular calcium and osteocalcin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinate nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalent ions and its responsiveness to anabolic steroids.
Tissue specificity	Isoform 1 is expressed at high level in brain, skeletal muscle, testis, bone, calvaria, osteoblasts and leukocytes. Expressed at intermediate level in liver, heart, kidney and spleen. Expressed at low level in lung, pancreas, placenta and ovary. Not detected in thymus, prostate, small intestine, tongue and colon. Isoform 1 and isoform 2 are expressed in kidney at the same level. Isoform 2 is expressed at lower level than isoform 1 in the other tissues.
Posttranslational modification	N-glycosylated.
Celluar localization	Plasma Membrane;
UniPort	Q5T6X5