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Rabbit Anti-TF2E2 Polyclonal Antibody#abs133446

Description

Catalog-specification	Delivery time	USD price
abs133446-100ug	1-2 Weeks	301.0
abs133446-50ug	1-2 Weeks	201.0

Please note that the price provided is only for your reference. For detailed pricing, we encourage you to get in touch with our sales representative, Vecent. It is important to clarify that the final cost may vary depending on the specific product or service you are interested in. Therefore, we highly recommend discussing your requirements with our knowledgeable and experienced team to ensure that you receive accurate and personalized pricing information. So, feel free to reach out to us at your convenience, and we will be happy to assist you with any queries you may have.

Overview
catalog	abs133446
Other names	TFIIE beta, also known as General Transcription Factor IIE Subunit 2 or GTF2E2, is a polypeptide that plays a crucial role in transcription initiation. With a molecular weight of approximately 34 kDa, TFIIE beta is an essential component of the transcription factor TFIIE complex. It is encoded by the T2EB_HUMAN gene and is also known by other names such as TF2E 2, TF2E2, TFIIE B, and Transcription Initiation Factor IIE Subunit Beta. TFIIE beta is involved in regulating the transcriptional machinery by facilitating the assembly and stabilization of the pre-initiation complex. It interacts with various transcription factors and RNA polymerase II to promote accurate transcription initiation. Understanding the function and structure of TFIIE beta is crucial for unraveling the complexities of gene regulation and transcriptional control. Further research and investigation are necessary to fully comprehend the intricate mechanisms in which TFIIE beta contributes to gene expression and cellular processes.
Source	Rabbit
Specificity	TF2E2 Antibody is capable of detecting total TF2E2 levels present in the body. Its specificity enables it to identify endogenous levels of TF2E2 with high accuracy. The detection of endogenous levels enables a better understanding of TF2E2 activity in the body, which is crucial for studying various biological processes in the human system. The antibody can be used for preclinical and clinical research to identify and monitor target proteins and their activities.
Species Reactivity	Human;Mouse
Predictive reaction species	Pig;Rabbit;Sheep;Bovine;Horse
Antigen	TF2E2
Application	The recommended dilution ranges for WB are 1:500 to 1:1000, for IHC are 1:50 to 1:200, for IF/ICC are 1:100 to 1:500, and for ELISA (peptide) are 1:20000 to 1:40000. These dilution ranges ensure optimal results based on the original text information.
Immunogen	A synthesized peptide.
MW	33 KD
Properties
Concentration	1mg/ml
purification	Through the utilization of SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure preservation, keep the product frozen at -20 °C for up to a year. It is important to avoid repeated freeze and thaw cycles, as this may compromise the integrity of the product.
Storage buffer	The storage condition for Rabbit IgG is at -20 °C in phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to note that this product is stable for 12 months starting from the date of receipt. Please ensure proper storage to maintain the quality of the IgG.
Target
Background	Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Celluar localization	Cytosol;Nucleus;
UniPort	P29084