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Rabbit Anti-MARVELD2 Polyclonal Antibody#abs139131

Description

Catalog-specification	Delivery time	USD price
abs139131-100ug	1-2 Weeks	301.0
abs139131-50ug	1-2 Weeks	201.0

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Overview
catalog	abs139131
Other names	MARVD2, also known as MARVEL (membrane associating) domain containing 2, is a protein that belongs to the family of MARVEL domain containing proteins. It is encoded by the FLJ30532 gene and is also known as MRVLDC2 or Tricellulin. MARVD2 plays an important role in cell adhesion and is found primarily in tight junctions. Its function is essential for maintaining epithelial cell barrier integrity, which is crucial for normal physiological function. Mutations in the DFNB49 gene, which encodes MARVD2, can lead to hearing loss. Overall, MARVD2 is an important protein with diverse functions in various cellular processes.
Source	Rabbit
Specificity	The MARVELD2 Antibody is designed to identify total MARVELD2 protein levels within an organism's system. This signal is derived from endogenous sources and is highly specific to MARVELD2.
Species Reactivity	Human;Mouse;Rat
Antigen	MARVELD2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human MARVELD2.
MW	64 kDa
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography using SulfoLink™ Coupling Resin was employed to purify the antiserum. A highly similar content can be generated by rearranging the original information as follows: The purification of the antiserum involved the utilization of SulfoLink™ Coupling Resin in peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	The storage temperature should be maintained at -20 °C for one year, and it is important to prevent the product from undergoing repeated freeze/thaw cycles.
Storage buffer	This product is Rabbit IgG, dissolved in phosphate buffered saline with a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. For storage, it should be kept at -20 °C. It is recommended to use this product within 12 months from the date of receipt to ensure its stability.
Target
Background	Plays a role in the formation of the epithelial barriers. The separation of the endolymphatic and perilymphatic spaces of the organ of Corti from one another by epithelial barriers is required for normal hearing.
Celluar localization	Plasma Membrane;
UniPort	Q8N4S9